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Harvard Medical School
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General Medical Questions
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Q: What are the possible causes of sudden joint pain (knees, hips, back, elbows), malaise, and temperature elevation (100.8F) in a healthy, physically active (frequent hiker) woman?
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The Trusted Source
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Robert H. Shmerling, M.D.

Robert H. Shmerling, M.D., is associate physician at Beth Israel Deaconess Medical Center and associate professor at Harvard Medical School. He has been a practicing rheumatologist for over 20 years at Beth Israel Deaconess Medical Center. He is an active teacher in the Internal Medicine Residency Program, serving as the Robinson Firm Chief. He is also a teacher in the Rheumatology Fellowship Program.

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February 26, 2009
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A:

There are many possible causes of your symptoms, including:

  • An infection
    Examples include viral infections (especially Parvovirus, hepatitis B or hepatitis C and influenza), bacterial infections (such as Lyme disease, sexually transmitted disease, or a blood stream infection)
  • An autoimmune disease
    These are conditions in which a person's immune system appears to normal tissues. Lupus is a good example but there are many others.
  • Crystal-induced arthritis
    Gout and pseudogout are disorders in which crystals deposit in one or more joints. This causes pain, swelling and, in many cases, fever. However, these conditions usually affect only one or a few joints and are rare in pre-menopausal women.
  • An allergic reaction
    For example, a reaction to a drug may cause fever and joint pain.

Of these, viral infections would be a common cause of the sudden symptoms you describe. Adults who develop parvovirus infection usually have some exposure to young children. This infection is most commonly seen among daycare workers or preschool teachers.

See your doctor for an evaluation. While many viral infections will go away without treatment, it's important to establish a diagnosis whenever possible. This may affect treatment and future screening.

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